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Prothrombin Polyclonal Antibody, 100ul[BT-AP07416] Enzyme-Linked Immunosorbent Assay (ELISA) upon stress to the ER

SKU: 3237808340

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USD141.00 USD179.00

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Prothrombin Polyclonal Antibody, 100ul[BT-AP07416] Enzyme-Linked Immunosorbent Assay (ELISA) upon stress to the ERCoagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia.

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Description

upon stress to the ER

Decreased expression of this gene may be associated with tumor growth and metastasis

which is a member of the X family of DNA polymerases

The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma

Prothrombin Polyclonal Antibody, 100ul[BT-AP07416] Enzyme-Linked Immunosorbent Assay (ELISA) upon stress to the ERCoagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia.

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