SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody, 100ul DNA Libraries Synthesis This protein functions as both

This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells| the thyroid| eye| liver and kidney

With 50 Units/μL of activity in just 50 μL

The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro

Mutations in this gene cause autosomal dominant severe congenital neutropenia

SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody, 100ul DNA Libraries Synthesis This protein functions as bothThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in