Peroxin 5 Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding the same protein have been found for this gene

A minor form (25 kDa) is the glycosylated form of the 22 kDa form

In small round cell sarcoma| this gene is fused to EWS by a small inversion of 22q| then the hybrid is thought to be translocated (t(1

Mutations in this gene are a cause of 3M syndrome-3 (3M3)

Peroxin 5 Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Two alternatively spliced transcript variantsThe product of PEX5 (peroxisomal biogenesis factor 5) binds to the C terminal PTS1 type tripeptide peroxisomal targeting signal (SKL type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in