LIMK-1/2(Phospho Thr508/505) Polyclonal Antibody, 100ul Cryopreservation Alternative promoter usage and splicing

Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2

Four transcript variants encoding three different isoforms have been found for this gene

Some of its substrates include transforming growth factor beta related proteins| proalbumin| and von Willebrand factor

eosinophils and natural killer cells

LIMK-1/2(Phospho Thr508/505) Polyclonal Antibody, 100ul Cryopreservation Alternative promoter usage and splicingThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase