Dvl-2 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding distinct isoforms have been reported

Alternatively spliced variants encoding different isoforms have been reported| but their biological validity has not been determined

Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome

The LRP2 protein is critical for the reuptake of numerous ligands

Dvl-2 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Alternatively spliced transcript variants encodingDVL2 encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. DVL2 encodes a 90 kD protein that undergoes posttranslational phosphorylation to form a 95 kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved