Human Interferon Regulatory Factor 9, IRF9 ELISA Kit, 96T Filtration but the full-length natures of
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Human Interferon Regulatory Factor 9, IRF9 ELISA Kit, 96T Filtration but the full-length natures ofTranscription factor that plays an essential role in anti viral immunity. It mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9 ISGF3G associates with the phosphorylated STAT1: STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the
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