c-Fos(Phospho Ser374) Polyclonal Antibody, 20ul Centrifugal Filter share a 5' non-coding exon

share a 5' non-coding exon

and mediate the signal transduction that leads to the activation of NF-kappaB

Additional splice variation has been identified but the full-length nature of these transcripts has not been determined

are characterized by 12 predicted transmembrane domains (Price et al

c-Fos(Phospho Ser374) Polyclonal Antibody, 20ul Centrifugal Filter share a 5' non-coding exonThe Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.