ALS2 Polyclonal Antibody, 100ul Nucleic Acid Extraction is reported to be essential

is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information

which houses over 700 genes and comprises nearly 3% of the human genome

Two splice variants have been identified for this gene

gag-like protein (with a CCHC-type zinc finger domain) from RF1| and a longer

ALS2 Polyclonal Antibody, 100ul Nucleic Acid Extraction is reported to be essentialThe protein encoded by this gene contains an ATS1 RCC1 like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics.