RUBIC Rabbit Polyclonal Antibody, 50ul Transporters This member contains six membrane-spanning

This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment

but also serve as scaffolding platforms for the assembly

Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function

and lead to the phosphorylation of glycogen synthase kinase-3

RUBIC Rabbit Polyclonal Antibody, 50ul Transporters This member contains six membrane-spanningThe protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains an N terminal RUN domain and a C terminal DUF4206 domain. The RUN domain is involved in Ras like GTPase signaling and the DUF4206 domain contains a diacylglycerol (DAG) binding like motif. Mutation in this gene results in deletion of the DAG binding like motif and causes a