Stat3(Phospho-Tyr705) Rabbit Polyclonal Antibody, 50ul Antisense Oligonucleotides It is an atypical calpain

It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain

Mutations in this gene have been found in patients with velocardiofacial syndrome

Contains 1 PHD-type zinc finger

This kinase activates certain potassium

Stat3(Phospho-Tyr705) Rabbit Polyclonal Antibody, 50ul Antisense Oligonucleotides It is an atypical calpainThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2.