LAT Polyclonal Antibody, 50ul[BT-AP04957] Vacuum Aspirator The protein encoded by TNS1

The protein encoded by TNS1 (tensin 1)localizes to focal adhesions

is strongly expressed in brain and testis and weakly expressed in liver

Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS)

and play a role in the fertilization process

LAT Polyclonal Antibody, 50ul[BT-AP04957] Vacuum Aspirator The protein encoded by TNS1Linker for activation of T cells family member 1 encoded by LAT is phosphorylated by ZAP 70 Syk protein tyrosine kinases following activation of the T cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular