HMG-17 (Acetyl Lys3) Rabbit Polyclonal Antibody, 100ul Plates & Dishes Alternatively spliced transcript variants that

Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described

This gene encodes a member the HERC ubiquitin ligase family

This gene potentially has a role in regulation of cell proliferation or differentiation

Diseases associated with GK2 include glycerol kinase deficiency and x-linked adrenal hypoplasia congenita

HMG-17 (Acetyl Lys3) Rabbit Polyclonal Antibody, 100ul Plates & Dishes Alternatively spliced transcript variants thatThe protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein HMGN1 the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria viruses and fungi.