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Ku-70 (Acetyl Lys317) Polyclonal Antibody, 100ul Capsule Filter The encoded protein may function

SKU: 34403012673

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Ku-70 (Acetyl Lys317) Polyclonal Antibody, 100ul Capsule Filter The encoded protein may functionThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

The encoded protein may function in regulation of alternative splicing and may play a role in the pathophysiology of myotonic dystrophy

meningocerebrovascular amyloidosis

They are also characterized by a catalytic triad composed of a histidine

The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2

Ku-70 (Acetyl Lys317) Polyclonal Antibody, 100ul Capsule Filter The encoded protein may functionThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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