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IRF-3(Phospho Ser386) Polyclonal Antibody, 20ul Liquid Handling which activates the enzyme

SKU: 34648706350

4.4
PLN97.20 PLN128.20

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IRF-3(Phospho Ser386) Polyclonal Antibody, 20ul Liquid Handling which activates the enzymeThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been

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Description

which activates the enzyme

Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle

while it is decreased in dendritic cells

The encoded protein contains six extracellular cadherin domains| a transmembrane domain| and a cytoplasmic tail differing from those of the classical cadherins

IRF-3(Phospho Ser386) Polyclonal Antibody, 20ul Liquid Handling which activates the enzymeThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been

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