PIASx Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) proliferation of endothelial cells

proliferation of endothelial cells

The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells

The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates

resulting from alternative splicing and encoding different isoforms

PIASx Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) proliferation of endothelial cellsPIAS2 encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PIAS2. Isoforms of protein inhibitor of activated STAT 2 enhance the sumoylation of specific target proteins including the p53 tumor