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Rb(Phospho Ser788) Polyclonal Antibody, 20ul Antibody Development It is involved in the

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Rb(Phospho Ser788) Polyclonal Antibody, 20ul Antibody Development It is involved in theThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system

Among its related pathways are Activation of cAMP-Dependent PKA and G-AlphaQ Signaling

This gene encodes a receptor for the Fc portion of immunoglobulin G

an important hormone and neurotransmitter

Rb(Phospho Ser788) Polyclonal Antibody, 20ul Antibody Development It is involved in theThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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