HAP1 Polyclonal Antibody, 20ul Thermo Mix E3 ubiquitin-protein ligase that mediates

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins

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A related pseudogene has been defined on chromosome 16

Rac GTPase activating protein 1 plays a regulatory role in cytokinesis

HAP1 Polyclonal Antibody, 20ul Thermo Mix E3 ubiquitin-protein ligase that mediatesHuntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase