Rat Urocortin, UCN LISA KIT, 96T Site-directed Mutagenesis The encoded protein promotes angiogenesis

The encoded protein promotes angiogenesis and endothelial cell growth

This gene encodes the gamma subunit

11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia

and has been shown to form dimers/oligomers through its leucine-zipper motif

Rat Urocortin, UCN LISA KIT, 96T Site-directed Mutagenesis The encoded protein promotes angiogenesisActs in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) (PubMed: 7477349). Binds with high affinity to CRF receptor types 1, 2 alpha, and 2 beta (By similarity). Plays a role in the establishment of normal hearing thresholds (By similarity). Reduces food intake and regulates ghrelin levels in gastric body and plasma (PubMed: 21540451).