LRC3B Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis in the chromosome 17q21 region

in the chromosome 17q21 region

This protein and RII PKA colocalize at the cell periphery

Defects in this gene are a cause of congenital disorder of glycosylation| type IIp

which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade

LRC3B Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis in the chromosome 17q21 regionThe protein encoded by this gene is a tumor suppressor with lowered expression levels found in gastric renal colorectal lung and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene.