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SCRIB Polyclonal Antibody, 50ul Cell Culture Several alternatively spliced transcript variants|

SKU: 35609591309

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SCRIB Polyclonal Antibody, 50ul Cell Culture Several alternatively spliced transcript variants|This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C terminus of E6. Two alternatively spliced transcript variants that encode different protein

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Description

Several alternatively spliced transcript variants| some of which encode distinct isoforms| have been identified

enabling recruitment and activation of intracellular signaling pathways in neurons

Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line

This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway

SCRIB Polyclonal Antibody, 50ul Cell Culture Several alternatively spliced transcript variants|This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C terminus of E6. Two alternatively spliced transcript variants that encode different protein

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