MIB1 Polyclonal Antibody, 50ul Culture Plate Inserts BECN1 (beclin 1) encodes a

BECN1 (beclin 1) encodes a protein that regulates autophagy

GO annotations related to this gene include poly (A) RNA binding and ligase activity

This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein family

Expressed in fetal heart

MIB1 Polyclonal Antibody, 50ul Culture Plate Inserts BECN1 (beclin 1) encodes aMIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death associated protein kinase 1 (DAPK1).