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PKR Polyclonal Antibody, 100ul[BT-AP07244] Buffers & Solutions This gene encodes the alpha

SKU: 35733074224

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PKR Polyclonal Antibody, 100ul[BT-AP07244] Buffers & Solutions This gene encodes the alphaThe protein encoded by EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms

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Description

This gene encodes the alpha subunit of C8

but the full-length nature of some variants has not been determined

Mutations in this gene are associated with ARCS2 (arthrogryposis| renal dysfunction| and cholestasis-2)

It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction

PKR Polyclonal Antibody, 100ul[BT-AP07244] Buffers & Solutions This gene encodes the alphaThe protein encoded by EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms

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