NFKappaB-p65 Polyclonal Antibody, 100ul[BT-AP05999] Micro Centrifuge Tubes An important paralog of this

An important paralog of this gene is PLP1

this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles

The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2| and expression of this gene may play a role in malignant transformation

Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC

NFKappaB-p65 Polyclonal Antibody, 100ul[BT-AP05999] Micro Centrifuge Tubes An important paralog of thisNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of RELA, RELA. Four