TNKS2 Polyclonal Antibody, 100ul Enzymes & Activity Assays Alternate splicing resultsi n multiple

Alternate splicing resultsi n multiple transcript variants

in particular during tumorigenesis

The protein encoded by this gene belongs to the actin family of proteins

The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol

TNKS2 Polyclonal Antibody, 100ul Enzymes & Activity Assays Alternate splicing resultsi n multipleCatalytic activity: NAD(+) + (ADP D ribosyl)(n) acceptor = nicotinamide + (ADP D ribosyl)(n+1) acceptor.,May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4 GLUT4 vesicles. Has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.,PTM: ADP ribosylated ( auto).,Contains 1 PARP catalytic domain.,Contains 1 SAM (sterile alpha motif) domain.,Contains 15 ANK repeats.,subcellular