CD58 Polyclonal Antibody, 100ul[BT-AP01958] Cellular Function Assays Its expression is induced by

Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis

SH3TC2 (SH3 domain and tetratricopeptide repeats 2) encodes a protein with two N-terminal Src homology 3 (SH3) domains and 10 tetratricopeptide repeat (TPR) motifs

in adults| significant expression is found in Schwann cells| meningeal cells| lens and nerve

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity

CD58 Polyclonal Antibody, 100ul[BT-AP01958] Cellular Function Assays Its expression is induced byCoagulation factor II (thrombin) receptor like 3 (F2RL3) is a member of the large family of 7 transmembrane region receptors that couple to guanosine nucleotide binding proteins. F2RL3 is also a member of the protease activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.