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NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody, 100ul[BT-AP13930] Cell Culture & Maintenance N-terminal part of this PTP

SKU: 36319739676

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NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody, 100ul[BT-AP13930] Cell Culture & Maintenance N-terminal part of this PTPThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines oxidant free radicals ultraviolet irradiation and

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Description

N-terminal part of this PTP contains two tandem Src homolog (SH2) domains

Gene expression is high during fetal development and in most tumors

and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation

NEUROD2 encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins

NFκB-p105/p50(Phospho Ser337) Polyclonal Antibody, 100ul[BT-AP13930] Cell Culture & Maintenance N-terminal part of this PTPThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines oxidant free radicals ultraviolet irradiation and

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