F111A Rabbit Polyclonal Antibody, 50ul Bacterial Expression tissue specificity:Mainly expressed in epithelial

tissue specificity:Mainly expressed in epithelial tissues such as kidney

Dysregulation of this gene has been associated with the growth and progression of certain cancers

Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified

2|q22) associated with T-cell acute lymphoblastic leukemia

F111A Rabbit Polyclonal Antibody, 50ul Bacterial Expression tissue specificity:Mainly expressed in epithelialThe protein encoded by this gene is cell cycle regulated and has nuclear localization. The C terminal half of the protein shares homology with trypsin like peptidases and it contains a PCNA interacting peptide (PIP) box that is necessary for its co localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects consistent with the demonstrated role for this gene in Simian Virus 40 (SV40)