SIK2 Polyclonal Antibody, 50ul Protein Research This gene is expressed not

This gene is expressed not only in T lymphocytes

The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues

and has higher inhibitory activity when phosphorylated

Multiple pseudogenes have been identified for this gene

SIK2 Polyclonal Antibody, 50ul Protein Research This gene is expressed notCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by phosphorylation on Thr 175 by STK11 in complex with STE20 related adapter alpha (STRAD alpha) pseudo kinase and CAB39.,Phosphorylates 'Ser 794' of IRS1 in insulin stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB specific