FRA1(Phospho-Ser265) Rabbit Polyclonal Antibody, 50ul Lysosome Component of the SCF(FBXW11) complex

Component of the SCF(FBXW11) complex containing FBXW11

Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity

differentiation and antioxidant functions

its capacity for calcium-binding may be absent or much lower than other family members

FRA1(Phospho-Ser265) Rabbit Polyclonal Antibody, 50ul Lysosome Component of the SCF(FBXW11) complexThe Fos gene family consists of 4 members: FOS FOSB FOSL1 and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family thereby forming the transcription factor complex AP 1. As such the FOS proteins have been implicated as regulators of cell proliferation differentiation and transformation. Several transcript variants encoding different isoforms have been found for this gene.