ABCB5 Monoclonal Antibody(11A2), 100ul Cellular Cultivation & Health Management This gene is specifically expressed

This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath

thus targeting specific proteins for lysosomal degradation

The tumor necrosis factor superfamily member 4 functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells

Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA

ABCB5 Monoclonal Antibody(11A2), 100ul Cellular Cultivation & Health Management This gene is specifically expressedABCB5 belongs to the ATP binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules.