BMP-10 Polyclonal Antibody, 50ul[BT-AP14461] Purification several human homologs of the

several human homologs of the ERD2 gene

Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus

May play a role in the uptake and recycling of iron| via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme

Transcript variants encoding different isoforms have been described for this gene

BMP-10 Polyclonal Antibody, 50ul[BT-AP14461] Purification several human homologs of theThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor like kinase 1 (ALK1) and plays important roles in