Tensin-1 Polyclonal Antibody, 50ul Peptide Modification This gene encodes a member

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors

and serves as a mediating factor for Ca (2+)- dependent inhibition of smooth muscle contraction

The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea

has been correlated with DLX3 gene mutation

Tensin-1 Polyclonal Antibody, 50ul Peptide Modification This gene encodes a memberThe protein encoded by TNS1 (tensin 1)localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms.