GHR Polyclonal Antibody, 100ul Cell Culture Dishes Their C-terminal EVH2 domain mediates

Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin

and contributes to T cell activation

The predicted protein is proline-rich and contains several dopamine D4 receptor signatures and PRINTS domains

It is expressed only in brain and ovary

GHR Polyclonal Antibody, 100ul Cell Culture Dishes Their C-terminal EVH2 domain mediatesGHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.