SMG7 Polyclonal Antibody, 20ul Custom Peptide Synthesis two pseudogenes

two pseudogenes

and in mouse it has been shown to be required for double-stranded RNA induction of these genes

It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage

The protein encoded by MYOZ2 (myozenin 2) belongs to a family of sarcomeric proteins that bind to calcineurin

SMG7 Polyclonal Antibody, 20ul Custom Peptide Synthesis two pseudogenesSMG7 encodes protein SMG7 that is essential for nonsense mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C terminal domain interacts with the mRNA decay