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FoxO4(Phospho Ser262) Polyclonal Antibody, 20ul Pathway and Network Analysis Mutations in this gene have

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FoxO4(Phospho Ser262) Polyclonal Antibody, 20ul Pathway and Network Analysis Mutations in this gene haveThis gene encodes a member of the O class of winged helix forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants

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Description

Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome

The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin

Alternatively spliced variants which encode different protein isoforms have been described| but only one has been fully characterized

nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription

FoxO4(Phospho Ser262) Polyclonal Antibody, 20ul Pathway and Network Analysis Mutations in this gene haveThis gene encodes a member of the O class of winged helix forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants

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