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MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath MED8 encodes a protein component

SKU: 38282045474

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MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath MED8 encodes a protein componentThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

MED8 encodes a protein component of the mediator complex

The protein encoded by this gene is the receptor for colony stimulating factor 1

It shares limited sequence similarity with iron-only bacterial hydrogenases

tongue and small intestine and in endocrine glands such as thyroid and adrenal gland

MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath MED8 encodes a protein componentThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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