Human Grb2-associated-binding Protein 2, GAB2 ELISA Kit, 96T Plasma providing reliable experimental results with

providing reliable experimental results with consistency

Binds to CCR9

This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells

Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation (PubMed: 18439902)

Human Grb2-associated-binding Protein 2, GAB2 ELISA Kit, 96T Plasma providing reliable experimental results withAdapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI 3 kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.