SNX17 Rabbit Polyclonal Antibody, 50ul Enzymes Mutations in this gene have

Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2

This gene encodes the alpha-1A subunit

This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits

and has been shown to form dimers/oligomers through its leucine-zipper motif

SNX17 Rabbit Polyclonal Antibody, 50ul Enzymes Mutations in this gene haveThis gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain which is a phosphoinositide binding domain and are involved in intracellular trafficking. This protein does not contain a coiled coil region like some family members but contains a B41 domain. This protein interacts with the cytoplasmic domain of P selectin and may function in the intracellular trafficking of P selectin. Alternative splicing