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Two transcript variants encoding different isoforms have been found for CBFB

Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis

Component of the probable ECS(SOCS3) complex with the substrate recognition component SOCS3

HEN1/2 Polyclonal Antibody, 100ul Gene Synthesis helping you reach your researchThe helix loop helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCL.