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RUNX1 Monoclonal Antibody, 100ul[BT-MCA1115] Buffer Solutions The encoded protein (ATR interacting

SKU: 38746267104

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RUNX1 Monoclonal Antibody, 100ul[BT-MCA1115] Buffer Solutions The encoded protein (ATR interactingCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have

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Description

The encoded protein (ATR interacting protein) binds to single-stranded DNA coated with replication protein A

such as CCNY

An important paralog of this gene is NPY1R

These mutations have been shown to cause diverse changes in the pattern of DNA methylation

RUNX1 Monoclonal Antibody, 100ul[BT-MCA1115] Buffer Solutions The encoded protein (ATR interactingCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have

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