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TPP1 Polyclonal Antibody, 50ul Dry Bath and may play a critical

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TPP1 Polyclonal Antibody, 50ul Dry Bath and may play a criticalThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto proteolyzed upon acidification. Mutations in this gene result in late infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific

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Description

and may play a critical role in glutathione homeostasis

Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways

Mutations in this gene are associated with microcephaly primary type 5

Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described

TPP1 Polyclonal Antibody, 50ul Dry Bath and may play a criticalThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto proteolyzed upon acidification. Mutations in this gene result in late infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific

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