Bax Polyclonal Antibody, 100ul[BT-AP06693] Stepper Mutations in this gene have

Mutations in this gene have been associated with medulloblastomas| secretory breast carcinomas and other cancers

Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER)

the gene also contains sequence encoding calcium-binding motifs found in all cadherins

Bax Polyclonal Antibody, 100ul[BT-AP06693] Stepper Mutations in this gene haveThe protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero or homodimers and act as anti or pro apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage dependent anion