FOXN1 Polyclonal Antibody, 100ul Centrifugal Filter Alternatively spliced transcript variants have
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FOXN1 Polyclonal Antibody, 100ul Centrifugal Filter Alternatively spliced transcript variants haveMutations in the winged helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T cell immunodeficiency, the skin
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