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Prothrombin Polyclonal Antibody, 20ul[BT-AP07415] Nucleic Acid Isolation & Purification Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
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Prothrombin Polyclonal Antibody, 20ul[BT-AP07415] Nucleic Acid Isolation & Purification Ectonucleotide pyrophosphatase/phosphodiesterase family member 2Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia.
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