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PNK1(Phospho-Ser114/Thr118) Rabbit Polyclonal Antibody, 100ul Biomatrix The encoded protein functions as

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PNK1(Phospho-Ser114/Thr118) Rabbit Polyclonal Antibody, 100ul Biomatrix The encoded protein functions asThis locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly seizures and developmental delay.

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Description

The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex

Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA

Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin

The active site residues of carboxypeptidases A and B are conserved in this protein

PNK1(Phospho-Ser114/Thr118) Rabbit Polyclonal Antibody, 100ul Biomatrix The encoded protein functions asThis locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly seizures and developmental delay.

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