DFNA5 Polyclonal Antibody, 100ul Drug Development and Evaluation VRK3 (vaccinia related kinase 3)

VRK3 (vaccinia related kinase 3) encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases

a disorder characterized by severely reduced brain size and mental retardation

Cytochrome P450 2C8/9/18/19 localizes to the endoplasmic reticulum but its specific substrate has not yet been determined

Cleavage stimulation factor subunit 2 is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs

DFNA5 Polyclonal Antibody, 100ul Drug Development and Evaluation VRK3 (vaccinia related kinase 3)Hearing impairment is a heterogeneous condition with over 40 loci described. Non syndromic hearing impairment protein 5 encoded by DFNA5 is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.