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Cbl Polyclonal Antibody, 50ul[BT-AP01263] Cell fragmentation and collection delaying the onset of anaphase

SKU: 40200666482

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SEK162.00 SEK182.00

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Cbl Polyclonal Antibody, 50ul[BT-AP01263] Cell fragmentation and collection delaying the onset of anaphaseCBL is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein (Cbl proto oncogene) is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated

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Description

delaying the onset of anaphase and ensuring proper chromosome segregation

Aberrant expression of this gene in adult tissues is associated with tumorigenesis

It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p

This gene encodes a protein that contains a leucine zipper motif

Cbl Polyclonal Antibody, 50ul[BT-AP01263] Cell fragmentation and collection delaying the onset of anaphaseCBL is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein (Cbl proto oncogene) is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated

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