Filamin 1(Phospho Ser2152) Polyclonal Antibody, 100ul Gloves The sialic acid binding Ig

The sialic acid binding Ig like lectin 1 is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner

FAM48A is required for MAP kinase p38 activation during gastrulation and for starvation-induced ATG9A trafficking during autophagy

It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors

Low level of expression seen in the liver| thymus| and peripheral blood leukocytes

Filamin 1(Phospho Ser2152) Polyclonal Antibody, 100ul Gloves The sialic acid binding IgThe protein encoded by this gene is an actin binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias