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TGF Beta RI Polyclonal Antibody, 50ul Vector Construction also known as the transferrin

SKU: 41756331119

4.2
USD185.00 USD226.00

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TGF Beta RI Polyclonal Antibody, 50ul Vector Construction also known as the transferrinTGF beta receptor type 1 encoded by TGFBR1 forms a heteromeric complex with type II TGF beta receptors when bound to TGF beta, transducing the TGF beta signal from the cell surface to the cytoplasm. The TGF beta receptor type 1 is a serine threonine protein kinase. Mutations in this gene have been associated with Loeys Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

also known as the transferrin receptor (TFR)

Histone acetylation and deacetylation are catalyzed by multisubunit complexes

enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

a calcium-binding epidermal growth factor-like domain

TGF Beta RI Polyclonal Antibody, 50ul Vector Construction also known as the transferrinTGF beta receptor type 1 encoded by TGFBR1 forms a heteromeric complex with type II TGF beta receptors when bound to TGF beta, transducing the TGF beta signal from the cell surface to the cytoplasm. The TGF beta receptor type 1 is a serine threonine protein kinase. Mutations in this gene have been associated with Loeys Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

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