EPAS-1 Polyclonal Antibody, 50ul Cell Labeling & Imaging Jagged 1 signalling through notch

Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis

This gene encodes an alpha isoform of the constant regulatory subunit A

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain

and dysequilibrium syndrome 3 (CMARQ3)

EPAS-1 Polyclonal Antibody, 50ul Cell Labeling & Imaging Jagged 1 signalling through notchEPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The endothelial PAS domain protein 1 contains a basic helix loop helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.